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1282513-77-2

1282513-77-2 Structure

1282513-77-2 Structure
IdentificationBack Directory
[Name]

β-NF-CH2-Br
[CAS]

1282513-77-2
[Synonyms]

β-NF-CH2-Br
β-NF-CH2-Br
β-Naphthoflavone-CH2-Br
β-Naphthoflavone-CH2-Br
3-(4-(Bromomethyl)phenyl)-1H-benzo[f]chromen-1-one
1H-Naphtho[2,1-b]pyran-1-one, 3-[4-(bromomethyl)phenyl]-
[Molecular Formula]

C20H13BrO2
[MDL Number]

MFCD34469967
[MOL File]

1282513-77-2.mol
[Molecular Weight]

365.22
Chemical PropertiesBack Directory
[Boiling point ]

517.2±50.0 °C(Predicted)
[density ]

1.503±0.06 g/cm3(Predicted)
Hazard InformationBack Directory
[Uses]

β-Naphthoflavone-CH2-Br (β-NF-CH2-Br) is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br can be used to synthesize the PROTAC β-NF-JQ1(HY-130256)[1].
[IC 50]

cIAP1
[References]

[1] Ohoka N, et al. Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins. ACS Chem Biol. 2019 Oct 16. DOI:10.1021/acschembio.9b00704
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