| Identification | Back Directory | [Name]
ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLN-VAL | [CAS]
128315-56-0 | [Synonyms]
MCH, RAT
MCH, HUMAN
MCH (HUMAN, MOUSE, RAT)
MCH (HUMAN) (RAT, MOUSE)
Melaninconcentratinghormone90%
MELANIN CONCENTRATING HORMONE 90%
MELANIN CONCENTRATING HORMONE RAT
Rat melanin-concentrating hormone
Human melanin-concentrating hormone
MELANIN-CONCENTRATING HORMONE, HUMAN
3: PN: WO0203070 SEQID: 6 claimed protein
1: PN: WO03060091 SEQID: 1 claimed protein
DFDMLRCMLGRVYRPCWQV (DISULFIDE BRIDGE: 7-16)
Melanin Concentrating Hormone (MCH)( Rat)
MELANIN CONCENTRATING HORMONE, HUMAN, MOUSE, RAT
MELANIN-CONCENTRATING HORMONE (HUMAN) (RAT, MOUSE)
Melanin-Concentrating Hormone (MCH) (human, mouse, rat)
Melanin concentrating hormone,human,mouse,rat, ≥90% (HPLC)
MCH (huMan, Mouse, rat)
Melanin-Concentrating HorMone (huMan, Mouse, rat)
ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLN-VAL
H-ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLN-VAL-OH
ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLN-VAL USP/EP/BP
H-Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Gln-Val-OH (Disulfide bond)
H-ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLN-VAL-OH (DISULFIDE BRIDGE: 7-16)
ASP-PHE-ASP-MET-LEU-ARG-CYS-MET-LEU-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLN-VAL: DFDMLRCMLGRVYRPCWQVDISULFIDE BRIDGE CYS7-CYS16
L-Valine, L-α-aspartyl-L-phenylalanyl-L-α-aspartyl-L-methionyl-L-leucyl-L-arginyl-L-cysteinyl-L-methionyl-L-leucylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-arginyl-L-prolyl-L-cysteinyl-L-tryptophyl-L-glutaminyl-, cyclic (7→16)-disulfide | [Molecular Formula]
C105H160N30O26S4 | [MDL Number]
MFCD00080193 | [MOL File]
128315-56-0.mol | [Molecular Weight]
2386.84 |
| Chemical Properties | Back Directory | [density ]
1.49±0.1 g/cm3(Predicted) | [RTECS ]
OS1748000 | [storage temp. ]
−20°C
| [form ]
Solid | [Water Solubility ]
Soluble to 1 mg/ml in water |
| Hazard Information | Back Directory | [Uses]
MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9?nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1]. | [storage]
Store at -20°C | [References]
[1] A W Sailer, et al. Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7564-9. DOI:10.1073/pnas.121170598 |
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