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128510-88-3

128510-88-3 Structure

128510-88-3 Structure
IdentificationBack Directory
[Name]

(R)-tert-Butyl 2-(tosyloxymethyl)pyrrolidine-1-carboxylate
[CAS]

128510-88-3
[Synonyms]

(R)-tert-Butyl 2-(tosyloxymethyl)pyrrolidine-1-carboxylate
tert-butyl (R)-2- ((tosyloxy)methyl)pyrroli dine-1-carboxylate
tert-Butyl (R)-2-[[[(4-Methylphenyl)sulfonyl]oxy]methyl]-1-pyrrolidinecarboxylate
2-[(4-methylphenyl)sulfonyloxymethyl]-1-pyrrolidinecarboxylic acid tert-butyl ester
tert-Butyl (2R)-2-({[(4-methylbenzene)sulfonyl]oxy}methyl)pyrrolidine-1-carboxylate
1-Pyrrolidinecarboxylicacid, 2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, 1,1-dimethylethyl ester,(2R)-
[Molecular Formula]

C17H25NO5S
[MDL Number]

MFCD11505914
[MOL File]

128510-88-3.mol
[Molecular Weight]

355.45
Chemical PropertiesBack Directory
[Boiling point ]

474.5±18.0 °C(Predicted)
[density ]

1+-.0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

-2.63±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

tert-Butyl (R)-2-[[[(4-Methylphenyl)sulfonyl]oxy]methyl]-1-pyrrolidinecarboxylate is an intermediate in the synthesis of (2S)-Ethylpyrrolidine Hydrochloride (E818080), which is used as a reagent in the synthesis of N,N''-substituted-1,3-diamino-2-hydroxypropanes for treating Alzheimer''s disease. Also used as a reagent in the synthesis of cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK kinase inhibitors for treatment of autoimmune disease, cancer, inflammatory disease, and other diseases.
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