| Identification | Back Directory | [Name]
lychnostatin 2 | [CAS]
128700-84-5 | [Synonyms]
lychnostatin 2
2-Propenoic acid, 2-methyl-, (3aS,4S,6R,10S,11aR)-6-(acetyloxy)dodecahydro-6,10-dimethyl-3-methylene-2,7-dioxocyclodeca[b]furan-4-yl ester | [Molecular Formula]
C21H28O7 | [MOL File]
128700-84-5.mol | [Molecular Weight]
392.44 |
| Hazard Information | Back Directory | [Uses]
Lychnostatin 2 exhibits cytotoxicity in cell P-388 with an ED50 of 0.19 μg/ml. Lychnostatin 2 can be used in research abour leukemia[1]. | [Definition]
ChEBI: A germacranolide isolated from Lychnophora antillana and has been shown to exhibit antineoplastic activity. | [References]
[1] Pettit GR, et al., Antineoplastic agents, 178. Isolation and structure of lychnostatins 1 and 2 from the South American Lychnophora antillana. J Nat Prod. 1990 Mar-Apr;53(2):382-90. DOI:10.1021/np50068a017 |
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