| Hazard Information | Back Directory | [Description]
Lu-AF11205 is a potent mGlu5 receptor positive allosteric modulator (PAM). | [Uses]
Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors. | [References]
[1] Fused thiazolyl alkynes as potent mGlu5 receptor positive allosteric modulators DOI:10.1016/j.bmcl.2013.05.070 |
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