| Identification | Back Directory | [Name]
RIPK2 inhibitor 1 | [CAS]
1290490-78-6 | [Synonyms]
RIPK2 inhibitor 1
Benzamide, 3-(benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]- | [Molecular Formula]
C25H22N4O2 | [MOL File]
1290490-78-6.mol | [Molecular Weight]
410.47 |
| Hazard Information | Back Directory | [Uses]
RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor. RIPK2-IN-3 inhibits recombinant truncated RIPK2 with an IC50 of 6.39 μM. RIPK2-IN-3 can be used for research of inflammation and cancer[1]. | [Biological Activity]
RIPK2 inhibitor 1 is a potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) th at potently inhibit NFKB activity and the proliferation of cancer cell lines. RIPK2 inhibitor 1 inhibits intestinal and lung inflammation in rodent models. | [storage]
Store at -20°C | [References]
[1] Shairaz BAKSH, et al. Ripk2 inhibitors. WO2019161495. |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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