| Identification | Back Directory | [Name]
AUTOCAMTIDE-2 | [CAS]
129198-88-5 | [Synonyms]
AUTOCAMTIDE-2
KKALRRQETVDAL
Autocamtide II
AUTOCAMTIDE-2 [KKALRRQETVDAL]
CAM KINASE II SELECTIVE SUBSTRATE
AUTOCAMTIDE-2-RELATED INHIBITOR PEPTIDE
8: PN: WO2004009562 PAGE: 49 unclaimed sequence
Autocamtide 2 trifluoroacetate salt, ≥97% (HPLC)
LYS-LYS-ALA-LEU-ARG-ARG-GLN-GLU-THR-VAL-ASP-ALA-LEU
H-LYS-LYS-ALA-LEU-ARG-ARG-GLN-GLU-THR-VAL-ASP-ALA-LEU-OH
LYS-LYS-ALA-LEU-ARG-ARG-GLN-GLU-THR-VAL-ASP-ALA-LEU: KKALRRQETVDAL
Autocamtide-2 H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH
L-Leucine,L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-a-glutamyl-L-threonyl-L-valyl-L-a-aspartyl-L-alanyl-
L-Leucine, L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-α-glutamyl-L-threonyl-L-valyl-L-α-aspartyl-L-alanyl-
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]hexanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoyl]amino]-4-carboxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-methylbutanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-4-methylpentanoic acid | [Molecular Formula]
C65H118N22O20 | [MDL Number]
MFCD00143639 | [MOL File]
129198-88-5.mol | [Molecular Weight]
1527.77 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [solubility ]
H2O: 1 mg/mL
| [form ]
powder
| [color ]
white
| [Sequence]
Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu |
| Hazard Information | Back Directory | [Uses]
Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. | [IC 50]
CaMK II | [storage]
Store at -20°C | [References]
[1] Wang YY, et al. The emerging role of CaMKII in cancer. Oncotarget. 2015 May 20;6(14):11725-34. DOI:10.18632/oncotarget.3955 |
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