| Identification | Back Directory | [Name]
ICI 211965 | [CAS]
129424-08-4 | [Synonyms]
ZM-211965
ICI 211965
2-[1-Methoxy-1-[3-[(2-naphthalenyl)methoxy]phenyl]propyl]thiazole
1-[3-(2-Naphtylmethoxy)phenyl]-1-(2-thiazolyl)propyl(methyl) ether
Thiazole, 2-[1-methoxy-1-[3-(2-naphthalenylmethoxy)phenyl]propyl]- | [Molecular Formula]
C24H23NO2S | [MDL Number]
MFCD00889527 | [MOL File]
129424-08-4.mol | [Molecular Weight]
389.51 |
| Chemical Properties | Back Directory | [Boiling point ]
544.2±50.0 °C(Predicted) | [density ]
1.190±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
2.77±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
ICI 211965 (ZM-211965) is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor. | [IC 50]
5-LPO | [References]
[1] Crawley GC, et al. Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors. J Med Chem. 1992 Jul 10;35(14):2600-9. DOI:10.1021/jm00092a010 |
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