| Identification | Back Directory | [Name]
4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- | [CAS]
129544-85-0 | [Synonyms]
3-(benzylthio)-5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazole
4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- | [Molecular Formula]
C22H19N3OS | [MOL File]
129544-85-0.mol | [Molecular Weight]
373.47 |
| Chemical Properties | Back Directory | [Boiling point ]
591.4±60.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [form ]
Solid | [pka]
0.75±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington's disease[1]. | [References]
[1]. Quinti L, et al. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models. Cell Chem Biol. 2016 Jul 21;23(7):849-861. |
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