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ChEBI:Minalrestat is a member of isoquinolines. | [in vivo]
Minalrestat (Oral gavage, 10 mg/kg/day, for 30 days) corrects the decreased microvascular reactivity in diabetic rats[1].
Minalrestat (Oral gavage, 10 mg/kg) restores the reduced number of leukocytes adhered and migrated leukocytes in postcapillary venules in diabetic rats[2].
| Animal Model: | Alloxan (40 mg/kg i.v.)-induced diabetic rats[1] | | Dosage: | 10 mg/kg/day | | Administration: | Oral gavage, for 30 days. | | Result: | Restored the decreased microvascular reactivity. |
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