| Identification | Back Directory | [Name]
Furo[3,4-c]pyridine-3,4(1H,5H)-dione,1,1,5-trimethyl- | [CAS]
129748-28-3 | [Synonyms]
Furo[3,4-c]pyridine-3,4(1H,5H)-dione,1,1,5-trimethyl- | [Molecular Formula]
C10H11NO3 | [MOL File]
129748-28-3.mol | [Molecular Weight]
193.199 |
| Hazard Information | Back Directory | [Uses]
Cerpegin, a pyridinone-fused c-lactone, is an inhibitor of 20S proteasome. Cerpegin can be used as a tranquillizer, anti-inflammatory, analgesic and antiulcer[1][2]. | [References]
[1] Anna Hovhannisyan, et al. New C(4)- and C(1)-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1571-80. DOI:10.1016/j.bmcl.2014.01.072
[2] K. Sivakumar, et al. Structure of cerpegin, a new alkaloid. Acta Cryst. (1990). C46, 839-841. |
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