| Identification | Back Directory | [Name]
16-phenoxy tetranor Prostaglandin F2α isopropyl ester | [CAS]
130209-78-8 | [Synonyms]
16-phenoxy tetranor Prostaglandin F2α isopropyl ester
16-phenoxy tetranor Prostaglandin F2.alpha. isopropyl ester
16-phenoxy tetranor Prostaglandin F2α isopropyl ester Exclusive | [Molecular Formula]
C25H36O6 | [MOL File]
130209-78-8.mol | [Molecular Weight]
432.55 |
| Chemical Properties | Back Directory | [Boiling point ]
577.8±50.0 °C(Predicted) | [density ]
1.173±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): .5 mg/ml | [pka]
13.57±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid. | [Uses]
15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments[1]. | [storage]
Store at -20°C |
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