130306-02-4

Directory

130306-02-4 Structure

Identification	Back Directory
[Name] (E)-2'-DEOXY-2'-(FLUOROMETHYLENE) CYTIDINE
[CAS] 130306-02-4
[Synonyms] tezaciabine (E)-2'-DEOXY-2'-(FLUOROMETHYLENE) CYTIDINE Cytidine, 2'-deoxy-2'-(fluoromethylene)-, (2'E)-
[Molecular Formula] C10H12FN3O4
[MDL Number] MFCD00893181
[MOL File] 130306-02-4.mol
[Molecular Weight] 257.22

Chemical Properties	Back Directory
[Boiling point ] 512.5±60.0 °C(Predicted)
[density ] 1.71±0.1 g/cm3(Predicted)
[storage temp. ] -80°C
[solubility ] DMSO : 200 mg/mL (777.54 mM; Need ultrasonic)
[form ] Solid
[pka] 12.50±0.60(Predicted)
[color ] Off-white to light yellow

[Uses]

Tezacitabine is used in the synthesis of inhibitors of ribonucleoside diphosphate reductase.

[in vivo]

Tezacitabine (100 mg/kg; intraperitoneal injection; daily; female nude mice) treatment inhibits tumor growth in HCT 116 tumor xenografts^[2].

Animal Model:	Female nude mice (7-9-week-old) injected with HCT 116 cells^[2]
Dosage:	100 mg/kg
Administration:	Intraperitoneal injection; daily; 14 days
Result:	Inhibited tumor growth in HCT 116 tumor xenografts.

[storage]

-80°C

130306-02-4 suppliers list

Company Name:	Watson Biotechnology Co.,Ltd
Tel:	+86-18186686046 +86-18186686046 , +86-18186686046
Website:	https://www.chemicalbook.com/manufacturer/cnwhwatson/

Company Name:	Amadis Chemical Company Limited
Tel:	571-89925085
Website:	http://www.amadischem.com

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840 18892239720
Website:	http://www.jm-bio.com/

Company Name:	Guangzhou Younan Technology Co., Ltd
Tel:	020-82000279 18988968278
Website:	http://www.ubiochem.cn/

Company Name:	Hangzhou Jinghao Biotechnology Co., LTD
Tel:	17513242016 17513242016
Website:	https://www.chemicalbook.com/ShowSupplierProductsList1421058/0.htm

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840 15801484223;
Website:	http://www.jm-bio.com/

Company Name:	Shanghai Yifei Biotechnology Co. , Ltd.
Tel:	021-65675885 18964387627
Website:	http://www.efebio.com

Company Name:	RD International Technology Co., Limited
Tel:	18024082417
Website:	www.ruidiresearch.com

Company Name:	Biosynth Biological Technology (Suzhou) Co Ltd
Tel:	51288865780
Website:	www.biosynth.com

Tags:130306-02-4 Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login