| Identification | Back Directory | [Name]
C2 DIHYDROCERAMIDE | [CAS]
13031-64-6 | [Synonyms]
N-ACETYL DIHYDROSPHINGOSINE
D-erythro-C2-DihydroceraMide
C2 Dihydroceramide (d18:0/2:0)
D-erythro-2-AcetaMido-1,3-octadecanediol
D-erythro-1,3-Dihydroxy-2-acetaMidooctadecane
N-[(1S,2R)-2-Hydroxy-1-(hydroxyMethyl)heptadecyl]acetaMide | [Molecular Formula]
C20H41NO3 | [MDL Number]
MFCD00236495 | [MOL File]
13031-64-6.mol | [Molecular Weight]
343.544 |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
118-119°C | [Boiling point ]
531.8±40.0 °C(Predicted) | [density ]
0.953±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Soluble in DMSO (up to 5 mg/ml, with warming). | [form ]
White solid | [pka]
14.27±0.20(Predicted) | [color ]
White | [Stability:]
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week. | [Cosmetics Ingredients Functions]
HAIR CONDITIONING
SKIN CONDITIONING | [InChI]
1S/C20H41NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(24)19(17-22)21-18(2)23/h19-20,22,24H,3-17H2,1-2H3,(H,21,23)/t19-,20+/m0/s1 | [InChIKey]
CRJGESKKUOMBCT-VQTJNVASSA-N |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
May be used as a negative control for C2 Ceramide | [Definition]
ChEBI: A dihydroceramide in which the ceramide acyl group is specified as acetyl. | [Description]
C2 Dihydroceramide (13031-64-6) is a negative control for C2-ceramide (cat.# 10-1181).1,2 Induces autophagy in a variety of cell types.3,4 | [References]
1) Bielawska et al. (1993) Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide; J. Biol. Chem. 268 26226
2) Obeid et al. (1993) Programmed cell death induced by ceramide; Science, 259 1769
3) Jiang et al. (2012) Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide; Int. J. Cancer, 130 685
4) Siddique et al. (2015) Dihydroceramides: From Bit Players to Lead Actors; J. Biol. Chem., 290 15371 |
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| Company Name: |
Alfa Chemistry
|
| Tel: |
1-516-6625404 |
| Website: |
https://www.alfa-chemistry.com |
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