| Identification | Back Directory | [Name]
HIV PROTEASE SUBSTRATE VI | [CAS]
130877-92-8 | [Synonyms]
HIV PROTEASE SUBSTRATE VI
ARG-VAL-NLE-P-NITRO-PHE-GLU-ALA-NLE-NH2
H-ARG-VAL-NLE-PHE(4-NO2)-GLU-ALA-NLE-NH2
H-ARG-VAL-NLE-P-NITRO-PHE-GLU-ALA-NLE-NH2
L-Norleucinamide, L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-α-glutamyl-L-alanyl- (9CI) | [Molecular Formula]
C40H66N12O11 | [MDL Number]
MFCD00237107 | [MOL File]
130877-92-8.mol | [Molecular Weight]
891.03 |
| Chemical Properties | Back Directory | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
-15°C | [pka]
4.43±0.10(Predicted) | [Sequence]
Arg-Val-{Nle-p-nitro}-Phe-Glu-Ala-{Nle}-NH2 |
| Hazard Information | Back Directory | [Uses]
Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate of HIV-1 protease. Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 can be used to test HIV-1 protease activity[1]. | [References]
[1] Schramm HJ, et, al. Lipopeptides as dimerization inhibitors of HIV-1 protease. Biol Chem. 1999 May;380(5):593-6. DOI:10.1515/BC.1999.076 |
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