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1309435-78-6

1309435-78-6 Structure

1309435-78-6 Structure
IdentificationBack Directory
[Name]

(S)-3-(4-((5-((2,3-DIHYDROSPIRO[INDENE-1,4-PIPERIDIN]-1-YL)METHYL)THIOPHEN-2-YL)METHOXY)PHENYL)HEX-4-YNOIC ACID
[CAS]

1309435-78-6
[Synonyms]

(S)-3-(4-((5-((2,3-DIHYDROSPIRO[INDENE-1,4-PIPERIDIN]-1-YL)METHYL)THIOPHEN-2-YL)METHOXY)PHENYL)HEX-4-YNOIC ACID
[Molecular Formula]

C31H34NO3S
[MDL Number]

MFCD30829538
[MOL File]

1309435-78-6.mol
[Molecular Weight]

500.672
Hazard InformationBack Directory
[Description]

LY2922083 is a Potent and Selective GPR40 Agonist for the Treatment of Type 2 Diabetes Mellitus. LY2922083 demonstrated potent, efficacious and durable dose dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion during preclinical testing. The G protein-coupled receptor 40 (GPR40) also known as Free Fatty Acid Receptor 1 (FFAR1) is highly expressed in pancreatic, islet beta-cells and responds to endogenous fatty acids resulting in amplification of insulin secretion only in the presence of elevated glucose levels.
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