| Identification | Back Directory | [Name]
BWMISRWJRUSYEX-YOVIYTQZSA-N | [CAS]
1310012-15-7 | [Synonyms]
BWMISRWJRUSYEX-YOVIYTQZSA-N
Terbinafine-d3HCl (N-methyl-d3) | [Molecular Formula]
C21H26ClN | [MDL Number]
MFCD19705110 | [MOL File]
1310012-15-7.mol | [Molecular Weight]
327.9 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 14 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml | [form ]
A solid | [color ]
White to off-white | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
Terbinafine-d3 is intended for use as an internal standard for the quantification of terbinafine by GC- or LC-MS. Terbinafine is a broad-spectrum antifungal agent that has activity against T. rubrum, T. mentagrophytes, T. verrucosum, E. floccosum, M. canis, A. fumigatus, and S. schenckii (MIC50s = 0.003-0.8 μg/ml). It selectively inhibits C. albicans squalene epoxidase over rat liver epoxidase (IC50s = 0.03 and 77 μM, respectively). Terbinafine (90-120 μM) induces cell cycle arrest at the G0/G1 phase in COLO 205 tumor cells and human umbilical vein endothelial cells (HUVECs). Formulations containing terbinafine have been used in the treatment of nail and skin fungal infections. | [Uses]
Terbinafine-d3 HCl (N-methyl-d3) (CAS# 1310012-15-7) is a useful isotopically labeled research compound. |
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