1313407-95-2

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1313407-95-2 Structure

Identification	Back Directory
[Name] ARRY382
[CAS] 1313407-95-2
[Synonyms] ARRY382 RRY-382 ARRY-382 ARRY 382,ARRY382 N-(3-cyclopropyl-1-((6-methylpyridin-2-yl)methyl)-1H-indazol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)imidazo[1,2-a]pyridine-3-carboxamide Imidazo[1,2-a]pyridine-3-carboxamide, N-[3-cyclopropyl-1-[(6-methyl-2-pyridinyl)methyl]-1H-indazol-4-yl]-7-[2-(4-methyl-1-piperazinyl)ethoxy]-
[Molecular Formula] C32H36N8O2
[MDL Number] MFCD32709977
[MOL File] 1313407-95-2.mol
[Molecular Weight] 564.68

Chemical Properties	Back Directory
[density ] 1.37±0.1 g/cm3(Predicted)
[solubility ] Acetonitrile: Soluble DMSO: Soluble
[form ] Solid
[pka] 10.33±0.50(Predicted)

Hazard Information	Back Directory
[Uses] ARRY-382 is a potent, oral and highly selective inhibitor of CSF1R/c-Fms with an IC50 of 9 nM. ARRY-382 can be used for the research of advanced or metastatic cancers[1].
[References] [1] David K Edwards V, et al. Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples. Oncotarget. 2018 May 15;9(37):24576-24589. DOI:10.18632/oncotarget.25191

Spectrum Detail	Back Directory
[Spectrum Detail] ARRY382(1313407-95-2)¹HNMR

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