| Identification | Back Directory | [Name]
ICMT-IN-5 | [CAS]
1313602-92-4 | [Synonyms]
ICMT-IN-5
2H-Pyran-4-ethanamine, N-(2-fluoro-4-methylphenyl)tetrahydro-2,2-dimethyl-4-phenyl- | [Molecular Formula]
C22H28FNO | [MOL File]
1313602-92-4.mol | [Molecular Weight]
341.46 |
| Hazard Information | Back Directory | [Uses]
ICMT-IN-5 (compound 46) is an inhibitor of ICMT (IC50=0.3 μM)[1]. | [References]
[1] Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT). J Med Chem. 2011 Jul 28;54(14):5031-47. DOI:10.1021/jm200249a |
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