| Identification | Back Directory | [Name]
E 5090 | [CAS]
131420-91-2 | [Synonyms]
E 5090
E-5090【pharmaceutical】
(Z)-3-(4-Acetoxy-3-methoxy-5-ethyl-1-naphthalenyl)-2-methylpropenoic acid
(Z)-3-(4-Acetoxy-5-ethyl-3-methoxy-1-naphthalenyl)-2-methylpropenoic acid | [MDL Number]
MFCD00892949 | [MOL File]
131420-91-2.mol |
| Hazard Information | Back Directory | [Description]
E5090, a novel orally active inhibitor of IL-1 generation, has antiinflammatory properties. | [Uses]
E5090 is an orally active inhibitor of IL-1 generation which is converted in vivo into the pharmacologically active deacetylated form (DA-E5090). E5090 can be utilized in immunology research[1]. | [IC 50]
IL-1 | [References]
[1] Goto M, et al. A novel inhibitor of IL-1 generation, E5090: in vitro inhibitory effects on the generation of IL-1 by human monocytes. Agents Actions Suppl. 1991;32:225-9. DOI:10.1007/978-3-0348-7405-2_30 |
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