| Identification | Back Directory | [Name]
Ara-C triphosphate | [CAS]
13191-15-6 | [Synonyms]
Ara-C triphosphate
Cytarabine triphosphate
Arabinofuranosylcytosine Triphosphate
ara-Cytidine-5'-triphosphate (ara-CTP)
Ara-cytidine-5'-triphosphate (ara-CTP) (aqueous solution)
2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]- | [Molecular Formula]
C9H16N3O14P3 | [MOL File]
13191-15-6.mol | [Molecular Weight]
483.16 |
| Chemical Properties | Back Directory | [Boiling point ]
849.2±75.0 °C(Predicted) | [density ]
2.50±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
0.97±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Cytarabine triphosphate (Ara-CTP), an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine[1]. | [References]
[1] Anderson E, et, al. Intracellular cytarabine triphosphate in circulating blasts post-treatment predicts remission status in patients with acute myeloid leukemia. Exp Hematol. 2019 Jun;74:13-18.e3. DOI:10.1016/j.exphem.2019.04.005 |
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