| Identification | Back Directory | [Name]
JWH 018 N-pentanoic acid metabolite-d4 | [CAS]
1320363-49-2 | [Synonyms]
BYIVGHIYNFQIJX-NZLXMSDQSA-N
JWH 018 N-pentanoic acid metabolite-d4
JWH-018 N-pentanoic acid metabolite-d5 (alkylchain d4) | [Molecular Formula]
C24H21NO3 | [MDL Number]
MFCD18428072 | [MOL File]
1320363-49-2.mol | [Molecular Weight]
371.44 |
| Hazard Information | Back Directory | [Description]
JWH 018 N-pentanoic acid metabolite-d4 contains four deuterium atoms at the 3, 3’, 4, and 4’ positions. It is intended for use as an internal standard for the quantification of JWH 018 N-pentanoic acid metabolite by GC- or LC-mass spectrometry (MS). JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06. JWH 018 is one of several synthetic CBs which have been included in smoking mixtures. JWH 018 N-pentanoic acid metabolite is a minor urinary metabolite of JWH 018, characterized by carboxylation of the N-alkyl chain. In urine samples, this metabolite is almost completely glucuronidated. |
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