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132392-39-3

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132392-39-3 Structure

132392-39-3 Structure
IdentificationBack Directory
[Name]

LY 221068
[CAS]

132392-39-3
[Synonyms]

LY 221068
5-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-3-(dimethylamino)thiazolidin-4-one
[Molecular Formula]

C20H30N2O2S
[MDL Number]

MFCD00896439
[MOL File]

132392-39-3.mol
[Molecular Weight]

362.53
Chemical PropertiesBack Directory
[Boiling point ]

459.8±55.0 °C(Predicted)
[density ]

1.15±0.1 g/cm3(Predicted)
[pka]

11.15±0.50(Predicted)
Hazard InformationBack Directory
[Description]

LY 221068 is a potent antioxidant with antiinflammatory properties.
[Uses]

LY221068 is an anti-oxidant and an orally active, potent inhibitor of iron-dependent lipid peroxidation and 5-lipoxygenase with antiinflammatory properties. LY221068 inhibits bone damage and paw swelling in the Freund's Complete adjuvant (HY-153808) induced arthritis (FCA) model of rats. LY221068 is promising for research of arthritis[1].
[References]

[1] Panetta JA, et al. Anti-inflammatory effects of LY221068 and LY269415. Agents Actions. 1991 Sep;34(1-2):100-2. DOI:10.1007/BF01993249
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