| Identification | Back Directory | [Name]
N-(3-Hydroxybutanoyl)-L-homoserine lactone | [CAS]
1325550-06-8 | [Synonyms]
3-Hydroxy-C4-HSL
N-[(RS)-3-HYDROXYBUTYRYL]-L-HOMOSERI
3-Hydroxy-butanoyl-L-homoserine lactone
N-3-hydroxybutyryl-L-Homoserine lactone
N-(3-Hydroxybutanoyl)-L-homoserine lactone
N-[(RS)-3-Hydroxybutyryl]-L-homoserine lactone
Butanamide, 3-hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-
N-[(RS)-3-Hydroxybutyryl]-L-homoserine lactone >=96% (HPLC) | [Molecular Formula]
C8H13NO4 | [MDL Number]
MFCD30596559 | [MOL File]
1325550-06-8.mol | [Molecular Weight]
187.19 |
| Hazard Information | Back Directory | [Uses]
N-3-Hydroxybutyryl-L-homoserine lactone (3-OH-C4-HSL) is an acyl-homoserine lactone, that can be isolated from Vibrionaceae. N-3-Hydroxybutyryl-L-homoserine lactone is a signaling molecule that is involved in bacterial quorum sensing (QS). N-3-Hydroxybutyryl-L-homoserine lactone senses the density of bacterial population, regulates the cellular process, such as bioluminescence, biofilm formation, and exo-enzyme production[1]. | [Biochem/physiol Actions]
N-[(RS)-3-Hydroxybutyryl]-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation. | [storage]
Store at -20°C | [References]
[1] Purohit AA, et al., Presence of acyl-homoserine lactones in 57 members of the Vibrionaceae family. J Appl Microbiol. 2013 Sep;115(3):835-47. DOI:10.1111/jam.12264 |
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