ChemicalBook--->CAS DataBase List--->1326232-46-5

1326232-46-5

1326232-46-5 Structure

1326232-46-5 Structure
IdentificationBack Directory
[Name]

Anifrolumab
[CAS]

1326232-46-5
[Synonyms]

Anifrolumab
Research Grade Anifrolumab(DHD23001)
Anti-Human IFNAR1 Monoclonal Antibody(Anifrolumab)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Anifrolumab is a type I interferon (IFN) receptor antagonist, a human monoclonal antibody. Anifrolumab blocks the activity of type I interferon. Anifrolumab can be used in systemic lupus erythematosus (SLE) research[1][2].
[References]

[1] Furie R, et al. Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus. Arthritis Rheumatol. 2017 Feb;69(2):376-386. DOI:10.1002/art.39962
[2] Riggs JM, et al. Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus. Lupus Sci Med. 2018 Apr 5;5(1):e000261. DOI:10.1136/lupus-2018-000261
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