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132980-17-7

132980-17-7 Structure

132980-17-7 Structure
IdentificationBack Directory
[Name]

2,3-Dihydro-5-methoxy-6-methyl-1H-inden-2-amine Hydrochloride
[CAS]

132980-17-7
[Synonyms]

MMAI (hydrochloride)
5-methoxy-6-methyl-2,3-dihydro-1H-inden-2-amine:hydrochloride
2,3-Dihydro-5-methoxy-6-methyl-1H-inden-2-amine Hydrochloride
[Molecular Formula]

C11H16ClNO
[MDL Number]

MFCD28016675
[MOL File]

132980-17-7.mol
[Molecular Weight]

213.704
Chemical PropertiesBack Directory
[Melting point ]

316-317 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
[solubility ]

DMF: 1 mg/ml; DMSO: 20 mg/ml; Ethanol: 0.5 mg/ml; PBS (pH 7.2): 0.2 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

MMAI is a psychoactive aminoindan which can be found in recreational drug mixtures. It potently inhibits serotonin uptake (IC50 = 212 nM) and stimulates its release without inducing the neurotoxicity induced by 3,4-methylenedioxy methamphetamine and similar compounds. This product is intended for forensic and research applications.
[Uses]

2,3-Dihydro-5-methoxy-6-methyl-1H-inden-2-amine is an highly selective serotonin releasing agent and produces entactogen effects.
[References]

[1] P.D. SAINSBURY. Aminoindanes—the next wave of ‘legal highs’?[J]. Drug Testing and Analysis, 2011, 3 7-8: 479-482. DOI: 10.1002/dta.318
[2] MICHAEL P. JOHNSON. Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA)[J]. Journal of Medicinal Chemistry, 1991, 34 5: 1662-1668. DOI: 10.1021/jm00109a020
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