| Identification | Back Directory | [Name]
Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]- | [CAS]
133012-00-7 | [Synonyms]
LTB4-IN-1
Anti-inflammatory agent 2
Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]- | [Molecular Formula]
C26H30N2O4S | [MDL Number]
MFCD31544421 | [MOL File]
133012-00-7.mol | [Molecular Weight]
466.6 |
| Hazard Information | Back Directory | [Uses]
LTB4-IN-1 (Compound 6) is a leukotriene synthesis (LTB4) inhibitor with an IC50 of 70 nM[1]. | [IC 50]
LTB4: 70 nM (IC50) | [References]
[1] Hatzelmann A, et al. Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X1005 and other quinoline derivatives in intact cells and a cell-free system--implications for the function of 5-lipoxygenase activating protein. Biochem Pharmacol. 1994 Jun 15;47(12):2259-68. DOI:10.1016/0006-2952(94)90264-x |
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