| Identification | Back Directory | [Name]
2-methyl-1-(2,3,4,5,6-pentadeuteriophenyl)propan-2-amine:hydrochloride | [CAS]
1330236-21-9 | [Synonyms]
Phentermine-d5 (hydrochloride) (CRM)
Phentermine-d5 hydrochloride (phenyl-d5)
2-methyl-1-(2,3,4,5,6-pentadeuteriophenyl)propan-2-amine:hydrochloride | [Molecular Formula]
C10H11ClD5N | [MOL File]
1330236-21-9.mol | [Molecular Weight]
190.725 |
| Hazard Information | Back Directory | [Description]
Phentermine-d5 (CRM) is intended for use as an internal standard for the quantification of phentermine by GC- or LC-mass spectrometry. Phentermine is an α-methylated amphetamine that activates trace amine associated receptor 1 (TAAR1, EC50 = 5.47 μM). It potently stimulates the release of norepinephrine (IC50 = 39.4 nM), with less effect on the release of dopamine and serotonin (IC50s = 262 and 3,511 nM, respectively). Primarily through these actions, phentermine suppresses appetite and augments fat metabolism, supporting usefulness in ameliorating obesity. | [Uses]
Labelled Phentermine (P318830). An Amphetamine derivative.Controlled substance (stimulant). Anorexic. | [References]
[1] SEAN MANNING Nicholas F Andrea Pucci. Pharmacotherapy for obesity: novel agents and paradigms.[J]. Therapeutic Advances in Chronic Disease, 2014, 5 3: 135-148. DOI: 10.1177/2040622314522848
[2] NADIA FUCCI Nadia D G. Adulterants encountered in the illicit cocaine market[J]. Forensic science international, 1998, 95 3: Pages 247-252. DOI: 10.1016/s0379-0738(98)00102-9 |
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