ChemicalBook--->CAS DataBase List--->133029-32-0

133029-32-0

133029-32-0 Structure

133029-32-0 Structure
IdentificationBack Directory
[Name]

POLYAMINOPROPYL BIGUANIDE
[CAS]

133029-32-0
[Synonyms]

POLYAMINOPROPYL BIGUANIDE
POLYAMINE PROPYL BIGUANIDE
Polyaminopropyl biguanide, PAPB
N-(3-Aminopropyl)imidodicarbonimidic diamide homopolymer
Imidodicarbonimidic diamide, N-(3-aminopropyl)-, homopolymer
[EINECS(EC#)]

205-516-1
[Molecular Formula]

C5H14N6
[MOL File]

133029-32-0.mol
[Molecular Weight]

158.21
Chemical PropertiesBack Directory
[Cosmetics Ingredients Functions]

PRESERVATIVE
[InChI]

InChI=1S/C5H14N6/c6-2-1-3-10-5(9)11-4(7)8/h1-3,6H2,(H6,7,8,9,10,11)
[InChIKey]

XKFDVLUHBRJZQF-UHFFFAOYSA-N
[SMILES]

N(CCCN)C(=N)NC(N)=N
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H351-H400
[Precautionary statements ]

P201-P202-P281-P308+P313-P405-P501-P273-P391-P501
Hazard InformationBack Directory
[Uses]

Polyhexamethylene biguanide (PHMB) is an antiseptic with antiviral and antibacterial properties used in several ways including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners.
[Definition]

A hydrochloride salt of polyhexamethylene biguanide. It is a broad spectrum and fast acting bactericide which is used for the formulation of disinfectants and sanitisers.    
[Side effects]

PHMB (polyaminopropyl biguanide) proved toxic to keratocytes and was shown to have acute toxic effects in human cells where it caused severe inflammation, atherogenesis, and aging.
[Safety]

Polyaminopropyl Biguanide (PHMB) is not safe for consumers when used as a preservative in all cosmetic products up to the maximum concentration of 0.3%. The safe use could be based on a lower use concentration and/or restrictions with regard to cosmetic products' categories.
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