| Identification | Back Directory | [Name]
POLYAMINOPROPYL BIGUANIDE | [CAS]
133029-32-0 | [Synonyms]
POLYAMINOPROPYL BIGUANIDE
POLYAMINE PROPYL BIGUANIDE
Polyaminopropyl biguanide, PAPB
N-(3-Aminopropyl)imidodicarbonimidic diamide homopolymer
Imidodicarbonimidic diamide, N-(3-aminopropyl)-, homopolymer | [EINECS(EC#)]
205-516-1 | [Molecular Formula]
C5H14N6 | [MOL File]
133029-32-0.mol | [Molecular Weight]
158.21 |
| Chemical Properties | Back Directory | [Cosmetics Ingredients Functions]
PRESERVATIVE | [InChI]
InChI=1S/C5H14N6/c6-2-1-3-10-5(9)11-4(7)8/h1-3,6H2,(H6,7,8,9,10,11) | [InChIKey]
XKFDVLUHBRJZQF-UHFFFAOYSA-N | [SMILES]
N(CCCN)C(=N)NC(N)=N |
| Hazard Information | Back Directory | [Uses]
Polyhexamethylene biguanide (PHMB) is an antiseptic with antiviral and antibacterial properties used in several ways including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners. | [Definition]
A
hydrochloride salt of polyhexamethylene biguanide. It is a broad
spectrum and fast acting bactericide which is used for the formulation
of disinfectants and sanitisers. | [Side effects]
PHMB (polyaminopropyl biguanide) proved toxic to keratocytes and was shown to have acute toxic effects in human cells where it caused severe inflammation, atherogenesis, and aging. | [Safety]
Polyaminopropyl Biguanide (PHMB) is not safe for consumers when used as a preservative in all cosmetic products up to the maximum concentration of 0.3%. The safe use could be based on a lower use concentration and/or restrictions with regard to cosmetic products' categories. |
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