ChemicalBook--->CAS DataBase List--->133233-38-2

133233-38-2

133233-38-2 Structure

133233-38-2 Structure
IdentificationBack Directory
[Name]

Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2
[CAS]

133233-38-2
[Synonyms]

ABZ-THR-ILE-NLE-P-NITRO-PHE-GLN-ARG-NH2
18:PN:EP1382692 SEQID:19 claimed protein
L-Argininamide, N-(2-aminobenzoyl)-L-threonyl-L-isoleucyl-L-norleucyl-4-nitro-L-phenylalanyl-L-glutaminyl-
Anthranilyl-HIV Protease Substrate trifluoroacetate salt Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 trifluoroacetate salt
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S,3R)-2-[(2-aminobenzoyl)amino]-3-hydroxybutanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
[Molecular Formula]

C43H65N13O11
[MDL Number]

MFCD00143526
[MOL File]

133233-38-2.mol
[Molecular Weight]

940.06
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
[Sequence]

{Abz}-Thr-Ile-{Nle}-{p-nitro-Phe}-Gln-Arg-NH2
Hazard InformationBack Directory
[Uses]

Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay[1].
[References]

[1] Porter DJ, et al. Effectors of HIV-1 protease peptidolytic activity. Biochemistry. 2001 Sep 18;40(37):11131-9. DOI:10.1021/bi010418p
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