| Identification | Back Directory | [Name]
Pitstop 1 | [CAS]
1332879-51-2 | [Synonyms]
Pitstop 1
ClathrinIN1
Clathrin-IN-1
Clathrin IN 1
Clathrin inhibitor 1
Clathrin-inhibitor-1 | [Molecular Formula]
C19H15N2NaO5S | [MOL File]
1332879-51-2.mol | [Molecular Weight]
406.39 |
| Hazard Information | Back Directory | [Description]
Clathrin-IN-1 is a elective clathrin inhibitor. It acts by addressing clathrin function in cell physiology with potential applications as inhibitor of virus and pathogen entry and as modulator of cell signaling. | [Uses]
Pitstop 1 is a small molecule inhibitor with endocytosis-inhibiting activity. Pitstop 1 blocks the interaction of chaperones with the Krasin terminal domain in cells, thereby affecting the function of Krasin. Pitstop 1 exhibits superior biological activity in significantly inhibiting the effects of Krasin. Pitstop 1 acts as a dose that inhibits the entry of viruses and pathogens into cells and modulates cell signaling[1]. | [References]
[1] Development of 1,8-naphthalimides as clathrin inhibitors DOI:10.1021/jm4015263 |
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| Company Name: |
Abcam Limited
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021-2070050 400921018 |
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www.abcam.cn |
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