| Identification | Back Directory | [Name]
Peldesine | [CAS]
133432-71-0 | [Synonyms]
BCX 34
Peldesine
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-3,5-dihydro-7-(3-pyridinylmethyl)- | [Molecular Formula]
C12H11N5O | [MDL Number]
MFCD00866504 | [MOL File]
133432-71-0.mol | [Molecular Weight]
241.25 |
| Hazard Information | Back Directory | [Uses]
Antineoplastic; antipsoriatic. | [in vivo]
Oral bioavailability of Peldesine in rats is 76%. Peldesine is orally active in elevating plasma inosine in rats (2-fold at 30 mg/kg), in suppressing ex vivo RBC PNP activity in rats (98% at 3 h. 100 mg/kg), and in suppressing ex vivo skin PNP in mice (39% at 3 h, 100 mg/kg)[3]. |
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