1334532-25-0

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1334532-25-0 Structure

Identification	Back Directory
[Name] (3R)-4-[dimethyl(trideuteriomethyl)azaniumyl]-3-tetradecanoyloxybutanoate:hydrochloride
[CAS] 1334532-25-0
[Synonyms] Myristoyl-L-carnitine-d3 (chloride) L-CARNITINE:HCL, O-MYRISTOYL (N,N,N-TRIMETHYL-D9, 98%) (3R)-4-[dimethyl(trideuteriomethyl)azaniumyl]-3-tetradecanoyloxybutanoate:hydrochloride
[Molecular Formula] C21H32D9NO4·HCl
[MDL Number] MFCD32063383
[MOL File] 1334532-25-0.mol
[Molecular Weight] 411.034

Chemical Properties	Back Directory
[storage temp. ] Store at -20°C
[solubility ] DMF: 20 mg/ml,DMSO: 14 mg/ml,Ethanol: 20 mg/ml
[form ] A solid
[color ] White to off-white
[Stability:] Hygroscopic
[CAS Number Unlabeled] 173686-73-2

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H315-H319-H335
[Precautionary statements ] P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501

Hazard Information	Back Directory
[Description] Myristoyl-L-carnitine-d₃ is intended for use as an internal standard for the quantification of myristoyl-L-carnitine by GC- or LC-MS. Myristoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. Plasma levels of myristoyl-L-carnitine are decreased in patients with chronic fatigue syndrome and increased in patients with end-stage renal disease.
[Uses] Myristoyl-L-carnitine-d3 Hydrochloride is labelled Myristoyl-L-carnitine Hydrochloride (M884745), a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Lauroyl-L-carnitine can be diagnostic for a number of ?-oxidation defects.
[storage] Store at -20°C
[References] [1] STEPHANIE E REUTER. Impact of haemodialysis on individual endogenous plasma acylcarnitine concentrations in end-stage renal disease.[J]. Annals of Clinical Biochemistry, 2005, 42 Pt 5: 387-393. DOI: 10.1258/0004563054889954 [2] S. E. REUTER A. M E. Long-chain acylcarnitine deficiency in patients with chronic fatigue syndrome. Potential involvement of altered carnitine palmitoyltransferase-I activity[J]. Journal of Internal Medicine, 2010, 270 1: 76-84. DOI: 10.1111/j.1365-2796.2010.02341.x

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