ChemicalBook--->CAS DataBase List--->133605-57-9

133605-57-9

133605-57-9 Structure

133605-57-9 Structure
IdentificationBack Directory
[Name]

GLU-GLU-GLU-GLU-GLU-MET-ALA-VAL-VAL-PRO-GLN-GLY-LEU-PHE-ARG-GLY-NH2
[CAS]

133605-57-9
[Synonyms]

Pancreastatin 37-52
EEEEEMAVVPQGLFRG-NH2
PANCREASTATIN (37-52), HUMAN
PROSTAGLANDIN I2 METHYL ESTER
ChroMogranin A (286-301) (huMan)
CHROMOGRAININ A FRAGMENT 286-301
PANCREASTATIN FRAGMENT 37-52 HUMAN
CHROMOGRANIN A (HUMAN, 286-301 AMIDE) HYDROCHLORIDE
Pancreastatin (33-48) (huMan) ChroMogranin A (286-301) (huMan)
GLU-GLU-GLU-GLU-GLU-MET-ALA-VAL-VAL-PRO-GLN-GLY-LEU-PHE-ARG-GLY-NH2
H-GLU-GLU-GLU-GLU-GLU-MET-ALA-VAL-VAL-PRO-GLN-GLY-LEU-PHE-ARG-GLY-NH2
GLU-GLU-GLU-GLU-GLU-MET-ALA-VAL-VAL-PRO-GLN-GLY-LEU-PHE-ARG-GLY-NH2 HYDROCHLORIDE
Glycinamide, L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-methionyl-L-alanyl-L-valyl-L-valyl-L-prolyl-L-glutaminylglycyl-L-leucyl-L-phenylalanyl-L-arginyl- (9CI)
GLY-TRP-PRO-GLN-ALA-PRO-ALA-MET-ASP-GLY-ALA-GLY-LYS-THR-GLY-ALA-GLU-GLU-ALA-GLN-PRO-PRO-GLU-GLY-LYS-GLY-ALA-ARG-GLU-HIS-SER-ARG-GLN-GLU-GLU-GLU-GLU-GLU-THR-ALA-GLY-ALA-PRO-GLN-GLY-LEU-PHE-ARG-GLY-NH2: GWPQAPAMDGAGKTGAEEAQPPEGKGAREHSRQEEEEETAGAPQGLFRG-NH2
[Molecular Formula]

C78H123N21O27S
[MDL Number]

MFCD00080083
[MOL File]

133605-57-9.mol
[Molecular Weight]

1819
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[Sequence]

Glu-Glu-Glu-Glu-Glu-Met-Ala-Val-Val-Pro-Gln-Gly-Leu-Phe-Arg-Gly-NH2
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Pancreastatin (37-52), human is a pancreastatin fragment. Pancreastatin a CgA-derived peptide (CgA residues 250–301) with biological activity, inhibited the releasing of insulin by islet beta cells[1][2].
[References]

[1] Qiao XW, et al. Chromogranin A is a reliable serum diagnostic biomarker for pancreatic neuroendocrine tumors but not for insulinomas. BMC Endocr Disord. 2014 Aug 7;14:64. DOI:10.1186/1472-6823-14-64
[2] O'Dorisio TM, et al. Development of a highly sensitive and specific carboxy-terminal human pancreastatin assay to monitor neuroendocrine tumor behavior. Pancreas. 2010 Jul;39(5):611-6. DOI:10.1097/MPA.0b013e3181c68d7a
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