| Identification | Back Directory | [Name]
2,7-Phenanthrenediol, 1-[(4-hydroxyphenyl)methyl]-4-methoxy- | [CAS]
133740-30-4 | [Synonyms]
7-diol
1-(4-hydroxybenzyl)-4-methoxypenanthrene-2
1-(4-hydroxybenzyl)-4-methoxypenanthrene-2,7-diol
2,7-Phenanthrenediol, 1-[(4-hydroxyphenyl)methyl]-4-methoxy- | [Molecular Formula]
C22H18O4 | [MOL File]
133740-30-4.mol | [Molecular Weight]
346.376 |
| Hazard Information | Back Directory | [Uses]
BChE-IN-11 (compound 10) is a potent, selective and non-competitive BChE (butyrylcholinesterase) inhibitor, with an IC50 of 2.1 μM. BChE-IN-11 can be used for Alzheimer's disease (AD) research[1]. | [IC 50]
BChE: 2.1?±?0.3 μM (IC50); AChE | [References]
[1] Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649. DOI:10.1038/s41598-022-17912-7 |
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