1337920-46-3

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1337920-46-3 Structure

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[Description] RO5488608 is a new potent mGlu2/3 NAM.
[Uses] RO5488608 is a negative allosteric metabotropic modulator of glutamate receptor 2/3. RO5488608 inhibits LY354740 (HY-18941)-induced intracellular Ca2+ release and can be used for study of antidepressant[1].
[References] [1] Lundstr?m L, et al. Structural determinants of allosteric antagonism at metabotropic glutamate receptor 2: mechanistic studies with new potent negative allosteric modulators. Br J Pharmacol. 2011;164(2b):521-537. DOI:10.1111/j.1476-5381.2011.01409.x

1337920-46-3 suppliers list

Company Name:	Wuhan Han Sheng New Material Technology Co.，Ltd
Tel:	+8617798174412 , +8617798174412
Website:	www.hsnm.com.cn/

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