| Identification | Back Directory | [Name]
5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride | [CAS]
1338707-67-7 | [Synonyms]
5,6,7,8-TETRAHYDRO-1,7-NAPHTHYRIDINE HCL
5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride
1,7-Naphthyridine, 5,6,7,8-tetrahydro- (hydrochloride) | [Molecular Formula]
C8H11ClN2 | [MOL File]
1338707-67-7.mol | [Molecular Weight]
170.639 |
| Hazard Information | Back Directory | [Uses]
5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
5,6,7,8-Tetrahydro-[1,7]napthyridine hydrochloride. A methanolic solution (25 mL) of 7-Benzyl-5,6,7,8-tetrahydro-[1,7]naphthyridine (J. Het. Chem. 2001, 38, 535) (1.5g, 6.69 mmol) was degassed with argon for 20 min followed by the addition of 4N HCl in dioxane (2 mL) and Pd/C (300 mg, 20 wt%) and stirred under 50 psi hydrogen pressure at room temperature for 24h. After completion of the reaction the mixture was filtered on a short pad of celite and washed with methanol (4 × 25 mL). The filtrate was evaporated to dryness in vacuo and crystallized from methanol. Yield: 65% (calculated as 2HCl salt), 900 mg, yellowish solid. |
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Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
| Company Name: |
A.J Chemicals
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91-9810153283 |
| Website: |
www.ajchemicals.com |
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