| Chemical Properties | Back Directory | [Boiling point ]
583.9±60.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
10.47±0.29(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes[1]. | [IC 50]
CYP51 | [storage]
Store at -20°C | [References]
[1] Lockhart SR, et al. The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2528-31. DOI:10.1128/AAC.02770-15 |
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