| Identification | Back Directory | [Name]
N-[2-[(Acetyloxy)methoxy]-2-oxoethyl]-N-[2-[2-[5-[6-[(acetyloxy)methoxy]-3-oxo-3H-xanthen-9-yl]-2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]phenoxy]ethoxy]phenyl]glycine (acetyloxy)methyl ester | [CAS]
1345980-40-6 | [Synonyms]
Fluo-2 AM
Fluo-8, AM
Calcium Fluorescent Probe Fluo-8, AM
N-[2-[(Acetyloxy)methoxy]-2-oxoethyl]-N-[2-[2-[5-[6-[(acetyloxy)methoxy]-3-oxo-3H-xanthen-9-yl]-2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]phenoxy]ethoxy]phenyl]glycine (acetyloxy)methyl ester | [Molecular Formula]
C50H50N2O23 | [MDL Number]
MFCD26967980 | [MOL File]
1345980-40-6.mol | [Molecular Weight]
1046.93 |
| Chemical Properties | Back Directory | [Boiling point ]
1051.0±65.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO (up to 25 mg/ml). | [form ]
waxy solid | [pka]
1.56±0.50(Predicted) | [color ]
Dark | [Stability:]
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months. |
| Hazard Information | Back Directory | [Description]
FLUO-8 (AM) is a cell-permeable acetoxymethyl (AM) ester derivative of Fluo-8. Approximately twice as bright as Fluo-4. Absorbance 452 nm (26,000); Emission 515 nm (after AM hydrolysis; dissolved in 10 mM EGTA, 100 mM KCl, 10 mM MOPS, pH 7.2) | [Uses]
FLUO-8 (AM) is a green fluorescent calcium binding dye. It is a tool in making the determination of drug resistance in cells. | [References]
1) Minta et al. (1989), Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores; J. Biol. Chem., 264 8171 |
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