| Identification | Back Directory | [Name]
β-D-Glucopyranosiduronic acid, 3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl bis- | [CAS]
134869-04-8 | [Synonyms]
Fluorescein Di-β-D-Glucuronide
β-D-Glucopyranosiduronic acid, 3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl bis- | [Molecular Formula]
C32H28O17 | [MOL File]
134869-04-8.mol | [Molecular Weight]
684.56 |
| Hazard Information | Back Directory | [Uses]
Fluorescein Di-β-D-Glucuronide, a fluorescent probe, can be utilized to non-invasively image the intestinal bacterial β-glucuronidase activity in nude mice. Fluorescein Di-β-D-Glucuronide-based imaging reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, which would facilitate pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies[1]. | [References]
[1] Michael Chen, et al. Real-time imaging of intestinal bacterial β-glucuronidase activity by hydrolysis of a fluorescent probe. Sci Rep. 2017 Jun 9;7(1):3142. DOI:10.1038/s41598-017-03252-4 |
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| Company Name: |
Biorbyt Ltd.
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| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
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