| Identification | Back Directory | [Name]
9-(3-fluoro-2-phosphonylmethoxypropyl)adenine | [CAS]
135295-27-1 | [Synonyms]
(2RS)-FPMPA
9-(3-fluoro-2-phosphonylmethoxypropyl)adenine
(1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yloxy)methylphosphonic acid
Phosphonic acid, P-[[2-(6-amino-9H-purin-9-yl)-1-(fluoromethyl)ethoxy]methyl]- | [Molecular Formula]
C9H13FN5O4P | [MDL Number]
MFCD00905333 | [MOL File]
135295-27-1.mol | [Molecular Weight]
305.2 |
| Hazard Information | Back Directory | [Uses]
(2RS)-FPMPA can be used for synthesis of antiretroviral agents against HIV-1 and HIV-2[1]. | [References]
[1] Balzarini J, et al. 9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo. Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4961-5. DOI:10.1073/pnas.88.11.4961 |
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