| Identification | Back Directory | [Name]
2'-Amino-2'-deoxy-beta-D-arabino-5-methyl uridine | [CAS]
135304-48-2 | [Synonyms]
2'-Amino-2'-deoxy-b-D-arabino-5-methyluridine
2’-Amino-2’-deoxy-β-D-arabino-5-methyl uridine
2’-Amino-2’-deoxy-beta-D-arabino-5-methyluridine
2'-Amino-2'-deoxy-beta-D-arabino-5-methyl uridine
2,4(1H,3H)-Pyrimidinedione, 1-(2-amino-2-deoxy-β-D-arabinofuranosyl)-5-methyl- | [Molecular Formula]
C10H15N3O5 | [MOL File]
135304-48-2.mol | [Molecular Weight]
257.25 |
| Hazard Information | Back Directory | [Uses]
2’-Amino-2’-deoxy-β-D-arabino-5-methyl uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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