| Identification | Back Directory | [Name]
Restricticin | [CAS]
135357-96-9 | [Synonyms]
Ro-09-1470
Restricticin
Glycine [(2S)-tetrahydro-4β-methoxy-5β-methyl-2β-[(1E,3E,5E)-1-methyl-1,3,5-nonatrienyl]-2H-pyran]-3α-yl ester
Glycine, (2S,3R,4S,5S)-tetrahydro-4-methoxy-5-methyl-2-[(1E,3E,5E)-1-methyl-1,3,5-nonatrien-1-yl]-2H-pyran-3-yl ester | [Molecular Formula]
C19H31NO4 | [MDL Number]
MFCD00897402 | [MOL File]
135357-96-9.mol | [Molecular Weight]
337.457 |
| Hazard Information | Back Directory | [Description]
Restricticin is a naturally-occurring antifungal agent which contains triene, pyran and glycine ester functionalities. | [Uses]
Restricticin is a compound obtained from marine fungi, whose structure contains alkene, tetrahydropyran ring and glycine ester functional groups, and has anti-neuroinflammatory effects in lipopolysaccharide-induced BV-2 microglia by inhibiting the production of proinflammatory mediators. | [References]
[1] Anti-Neuroinflammatory Agent, Restricticin B, from the Marine-Derived Fungus Penicillium janthinellum and Its Inhibitory Activity on the NO Production in BV-2 Microglia Cells |
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