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1354567-82-0

1354567-82-0 Structure

1354567-82-0 Structure
IdentificationBack Directory
[Name]

Zotiraciclib diHCl (TG-02, SB-1317)
[CAS]

1354567-82-0
[Synonyms]

Zotiraciclib diHCl (TG-02, SB-1317)
[Molecular Formula]

C23H25ClN4O
[MOL File]

1354567-82-0.mol
[Molecular Weight]

408.93
Hazard InformationBack Directory
[Description]

Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9 (CDK9). It is one of a number of CDK inhibitors under investigation; others targeting CDK9 for the treatment of acute myeloid leukemia include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80 percent of glioblastomas characterized by this property.
1354567-82-0 suppliers list
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: InvivoChem  
Tel: 13549236410
Website: https://www.invivochem.cn/
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