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135575-42-7

135575-42-7 Structure

135575-42-7 Structure
IdentificationBack Directory
[Name]

Pneumocandin B0
[CAS]

135575-42-7
[EINECS(EC#)]

629-746-0
[Molecular Formula]

C50H80N8O17
[MDL Number]

MFCD28168025
[MOL File]

135575-42-7.mol
[Molecular Weight]

1065.22
Chemical PropertiesBack Directory
[Boiling point ]

1442.9±65.0 °C(Predicted)
[density ]

1.41±0.1 g/cm3(Predicted)
[pka]

9.86±0.26(Predicted)
[λmax]

276nm(MeOH)(lit.)
Hazard InformationBack Directory
[Uses]

Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, such as Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
[Uses]

Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from some species of Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
[Definition]

ChEBI: An echinocandin initially isolated as a very minor bioactive fermentation product of Glarea lozoyensis (originally known as Zalerion arboricola). Subsequent random mutagenesis work and optimisation of the fermentation medium permi ted the industrial production of pneumocandin B0, which is used as the starting point for the synthesis of the antifungal drug caspofungin.
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