| Identification | Back Directory | [Name]
Dnp-PYAYWMR (trifluoroacetate salt) | [CAS]
135662-06-5 | [Synonyms]
Dnp-pyaywmr trifluoroacetate
Dnp-PYAYWMR (trifluoroacetate salt)
L-Arginine, 1-(2,4-dinitrophenyl)-L-prolyl-L-tyrosyl-L-alanyl-L-tyrosyl-L-tryptophyl-L-methionyl-
1-(2,4-dinitrophenyl)-L-prolyl-L-tyrosyl-L-alanyl-L-tyrosyl-L-tryptophyl-L-methionyl-L-arginine,trifluoroacetatesalt | [Molecular Formula]
C54H65N13O14S | [MOL File]
135662-06-5.mol | [Molecular Weight]
1152.24 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Predicted) | [solubility ]
Formic Acid: 1 mg/ml | [pka]
3.29±0.10(Predicted) | [Sequence]
{DNP}-Pro-Tyr-Ala-Tyr-Trp-Met-Arg |
| Hazard Information | Back Directory | [Uses]
Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1]. | [References]
[1] Li Y, et al. Combination of serum matrix metalloproteinase-3 activity and EBV antibodies improves the diagnostic performance of nasopharyngeal carcinoma. J Cancer. 2020 Aug 18;11(20):6009-6018. DOI:10.7150/jca.46977 |
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