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1356943-67-3

1356943-67-3 Structure

1356943-67-3 Structure
IdentificationBack Directory
[Name]

Ethanone, 1-[6-(3-chloro-4-hydroxyphenyl)-4-[[4-(diethylamino)cyclohexyl]amino]-3-quinolinyl]-
[CAS]

1356943-67-3
[Synonyms]

OTS447
Ethanone, 1-[6-(3-chloro-4-hydroxyphenyl)-4-[[4-(diethylamino)cyclohexyl]amino]-3-quinolinyl]-
[Molecular Formula]

C27H32ClN3O2
[MOL File]

1356943-67-3.mol
[Molecular Weight]

466.01
Chemical PropertiesBack Directory
[Boiling point ]

620.0±55.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 12.41 mg/mL (26.63 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)
[form ]

Solid
[pka]

7.71±0.35(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

OTS447 is a potent FLT3 inhibitor with an IC50 of 21 nM (WO2012016082A1, compound 335)[1].
[References]

[1] Yo Matsuo, et al. Quinoline derivatives and melk inhibitors containing the same. WO2012016082A1.
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