| Identification | Back Directory | [Name]
ML-228 | [CAS]
1357171-62-0 | [Synonyms]
L-228
ML-228
CID-46742353
ML228; ML 228
ML-228;CID-46742353
N-([1,1'Biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine
N-([1,1-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
1,2,4-Triazin-5-amine, N-([1,1'-biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)- | [Molecular Formula]
C27H21N5 | [MDL Number]
MFCD26792570 | [MOL File]
1357171-62-0.mol | [Molecular Weight]
415.49 |
| Chemical Properties | Back Directory | [Boiling point ]
686.0±65.0 °C(Predicted) | [density ]
1.228±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C, Inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
2.03±0.63(Predicted) | [color ]
Pale Yellow to Light Yellow |
| Hazard Information | Back Directory | [Uses]
N-([1,1''-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine is an activator of the hypoxia inducible factor (HIF) pathway. | [Definition]
ChEBI: ML228 is a member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway. It has a role as a hypoxia-inducible factor pathway activator. It is a member of biphenyls, a member of 1,2,4-triazines, a secondary amino compound and a member of pyridines. |
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