| Identification | Back Directory | [Name]
Dolutegravir Impurity 6 | [CAS]
1357289-29-2 | [Synonyms]
Dolutegravir RR Isomer
Dolutegravir Impurity 6
Doultegravirr RR Isomer
Dolutegravir Impurity 42
(4R,12aR)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aR)- | [Molecular Formula]
C20H19F2N3O5 | [MOL File]
1357289-29-2.mol | [Molecular Weight]
419.38 |
| Hazard Information | Back Directory | [Uses]
Dolutegravir RR Isomer is an isomer of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. |
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