ChemicalBook--->CAS DataBase List--->136-70-9

136-70-9

136-70-9 Structure

136-70-9 Structure
IdentificationBack Directory
[Name]

protokylol
[CAS]

136-70-9
[Synonyms]

Jb 251
An 1031
protokylol
Protoquilol
Protokylolum
Protokylol [ban]
Einecs 205-255-3
136-69-6 (Hydrochloride)
1-(3,4-Dihydroxyphenyl)-2-(1-(3,4-methylendioxyphenyl)-2-propylamino)ethanol
1-(3,4-Dihydroxyphenyl)-2-(alpha-methyl-3,4-methylendioxyphenethylamino)ethanol
1,2-Benzenediol, 4-[2-[[2-(1,3-benzodioxol-5-yl)-1-methylethyl]amino]-1-hydroxyethyl]-
[EINECS(EC#)]

205-255-3
[Molecular Formula]

C18H21NO5
[MDL Number]

MFCD00864143
[MOL File]

136-70-9.mol
[Molecular Weight]

331.366
Chemical PropertiesBack Directory
[Melting point ]

126-127 °C
[Boiling point ]

585.0±45.0 °C(Predicted)
[density ]

1.336±0.06 g/cm3(Predicted)
[pka]

9.59±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Protokylol (Caytine; JB-251) is a beta-adrenergic receptor agonist and TRPV1 agonist. Protokylol is used as a bronchodilator[1].
[Definition]

ChEBI: Protokylol is a member of benzodioxoles.
[Brand name]

Ventaire (Sanofi Aventis).
[References]

[1] Corina Andrei, et al. In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity. Pharmaceutics. 2022 Nov 22;14(12):2563. DOI:10.3390/pharmaceutics14122563
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